SMONの重心動揺と中枢運動神経伝導時間 : 高齢者群との比較

Abstract

立位保持可能なSMON患者と高齢者に重心動揺検査を行い,その立位能を比較し,重心動揺に影響する因子について検討した。SMON患者を歩行能で2群に分けそれぞれを高齢者群と比較した場合,歩行能がより障害されている杖歩行群で,重心動揺距離,面積が有意に大きく,皮質脊髄路などの障害の指標となる中枢運動神経伝導時間も有意に遅延していた。SMON患者では中枢運動神経伝導時間と重心動揺距離が高い相関を示した。SMON患者のうち杖歩行群では重心動揺は大きくなり,CMCTの遅延と重心動揺の障害が並行して出現することが明らかにされた。

In 16 patients with SMON (group S) and 35 elderly healthy controls (group A), stabilograms were recorded for 15 seconds with the eyes open. Group S was divided into two subgroups : group S1, comprised of patients who did not need support in walking, and group S2, comprised of patients who required support in walking. Stability was statistically worse in group S2 than in groups A and S1, although there was no difference in stability between group S1 and group A. Similarly, central motor conduction time (CMCT) was prolonged in group S2, compared with groups A and S1. In group S, there was a good correlation between stability and CMCT ; the worse a patient's stability was, the slower CMCT was. In SMON, patients with disability in walking have worse stability than those without disability in walking. This finding suggests that impaired stability parallels central motor system impairment.